A quiet Saturday evening in Arizona turned into a nationwide emergency when 84-year-old Nancy Guthrie vanished from her home in Tucson.

For Savannah Guthrie ,longtime co-anchor of Today , February 2026 has become deeply personal. What began as a missing persons case has now evolved into a federal investigation, with authorities exploring the possibility of abduction.

Concern grew after Nancy failed to attend Sunday church, prompting a welfare check. According to  Chris Nanos , deputies found signs of forced entry and evidence of a struggle. A blood trail near the entrance heightened fears that she did not leave voluntarily.

Nancy’s family says she suffers from serious heart conditions and depends on daily medication, making her especially vulnerable. Investigators are also examining a reported ransom note sent to a local news outlet containing specific details about her home.

Tommaso Cioni, Savannah’s brother-in-law, was reportedly the last person to see Nancy after dropping her home Saturday night. Authorities say the family is fully cooperating.

Savannah has stepped away from her professional duties to be with loved ones, asking for privacy and prayers. Federal agents, including the FBI, have joined local law enforcement as the search intensifies.

As the investigation continues, hope remains urgent. The family—and community—wait anxiously for answers.